Understanding Test Results

Positive Test Results

A POSITIVE BLOOD TEST RESULT indicates that methylated Septin 9 DNA has been detected in the plasma sample tested. Methylated Septin 9 has been associated with the occurrence of colorectal cancer. Because Epi proColon^® 2.0 CE is not a confirmatory test for the presence of colorectal cancer, patients with positive Epi proColon^® 2.0 CE test results should be referred for diagnostic colonoscopy.

NOTE: Positive results have been observed in healthy patients and clinically diagnosed patients with chronic gastritis, esophagitis, non-rheumatoid arthritis, and lung, breast and prostate cancers and in pregnant women.

Negative Test Results

A NEGATIVE BLOOD TEST RESULT indicates the absence of methylated Septin 9 DNA in the plasma sample tested. Because a negative test result is not confirmatory for the absence of colorectal cancer, people should be advised to continue participating in a colorectal cancer screening program.